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Research Use Only
10 mg
≥99% purity

4.98/5 · 500+ researcher reviews

$59.99

$59.99

50% off

2 vials · $85.44 per vial

GHK-Cu

$59.99

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Research Use Only

All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Certificate of Analysis

Third-party tested for 99% purity, ID, quantity.

BATCH # RC0302-260402
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Every order is backed by full reship or refund coverage, including international shipments. All products are produced under documented lab procedures and ship with batch-verified COAs — what’s on the label is exactly what’s in the vial.

Overview

GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide studied for its role in molecular signaling, matrix remodeling, and pathway dynamics. In laboratory and preclinical models, GHK-Cu has been associated with modulation of gene expression, angiogenesis, and extracellular matrix activity, making it a valuable tool for research into experimental biology.

Pickart L. et al. (2015).

GHK was first identified in the 1970s in biological plasma samples, where it was observed to decline with age. Subsequent research demonstrated that complexing GHK with copper enhanced its biological activity, particularly in processes related to extracellular matrix dynamics and molecular remodeling. Over the years, GHK-Cu has been extensively studied in models of epithelial biology, angiogenesis, and systemic regulation of gene expression.

Pickart L., Margolina A. (2018).

CAS #: 89030-95-5

Molecular Formula: C₁₄H₂₄CuN₆O₄

Molecular Weight: 340.9 g/mol

PubChem ID: 5311476

Quantity: 10 mg per vial

Format: Sublingual liquid

Purity: ≥99% (qualifying batches)

GHK-Cu has been studied in structural, epithelial, and systemic models, with research highlighting its effects on collagen synthesis, extracellular matrix dynamics, and molecular remodeling. Studies also note its role in epithelial modeling, follicle signaling, and cytokine modulation in preclinical settings.

Key Areas of Research:
  • Structural: Collagen, matrix, connective signaling

  • Epithelial: Matrix dynamics, remodeling, follicle signaling

  • Systemic: Cytokine modulation, viability, pathway dynamics

Together, these findings suggest broad experimental potential for GHK-Cu across structural, epithelial, and systemic pathways. By supporting collagen formation and molecular remodeling while modulating cytokine signaling, GHK-Cu provides a versatile platform for research into matrix dynamics, epithelial biology, and systemic resilience in laboratory settings.

Pickart L. et al., 2015

Meet the compound

GHK-Cu, in a sublingual format

A naturally occurring copper-binding tripeptide, supplied for laboratory research in Rize's needle-free sublingual carrier.

What it is

  • Glycyl-L-histidyl-L-lysine bound to copper(II)
  • A naturally occurring tripeptide first identified in plasma in the 1970s
  • Studied for matrix remodeling and molecular signaling

The sublingual system

  • A Submagna, SNAC, DMSO and modified-Penetratin carrier matrix
  • Engineered for high bioavailability without needles
  • Permeation enhancers documented in peer-reviewed literature

How it's supplied

  • 10 mg per vial, sublingual liquid format
  • ≥99% purity on qualifying batches
  • Third-party COA ships with every order

Areas of research

Where GHK-Cu is studied

In laboratory and preclinical models, GHK-Cu has been associated with activity across three broad pathways. For research context only.

Structural

Collagen & matrix

Studied for effects on collagen synthesis, extracellular matrix dynamics, and connective signaling.

Epithelial

Remodeling & follicle signaling

Examined in models of epithelial biology, matrix dynamics, and molecular remodeling.

Systemic

Cytokine modulation

Investigated for cytokine modulation, cell viability, and broader gene-expression pathway dynamics.

Structure & specifications

The chemistry

CAS number 89030-95-5
Molecular formula C₁₄H₂₄CuN₆O₄
Molecular weight 340.9 g/mol
PubChem CID 5311476
Quantity 10 mg per vial
Format Sublingual liquid
Purity ≥99% (qualifying batches)

How every bottle is made
STEP 1

Sublingual formulation

Formulated with a Submagna, SNAC, DMSO and modified-Penetratin permeation matrix for needle-free delivery.

STEP 2

Verified purity

Every batch is third-party tested with HPLC and mass spectrometry for identity, purity, and endotoxins.

STEP 3

Same-day fulfillment

Orders dispatched same-day from our AUS and U.S. facility with tracked, temperature-considered shipping.

Every batch, four tests, documented

No lot is released until it clears third-party verification — documented in a COA that ships with every order.

Identity

Passed

Verifies the peptide's sequence and structure so the correct compound is present in each vial.

Purity

Passed

Measures purity and concentration to confirm ≥99% purity on qualifying batches.

Sterility

Passed

Screens for bacteria, fungi, and other microorganisms to verify sterile handling.

Endotoxin

Passed

Tests for lipopolysaccharides (LPS) to ensure endotoxin levels stay within research limits.

Frequently Asked Questions

Everything you need to know about our products and processes.

Are these for human consumption?

No. All Rize products are intended for research, laboratory, and analytical purposes only, and are not for human consumption of any kind.

Yes. Every batch undergoes strict third-party HPLC and mass spectrometry testing for purity, consistency, and quality before it ships. Certificates of analysis are public and verifiable by lot number.

All orders are processed and shipped same-day from our certified U.S. warehouse facility for fast, secure delivery.

Do you ship internationally?

Yes. We offer temperature-controlled international shipping to selected countries. Availability and delivery times vary by location.

Major credit and debit cards, PayPal, ACH bank transfer, and BTC — all through secure checkout.

Store in a fridge, away from direct sunlight and moisture. Refrigeration is recommended for long-term stability.

Order now, ships today

Save 10% on your first order. Research-grade purity, sublingual format, dispatched same-day from the USA.

INSTANT HPLC TRANSPARENCY

Verify Your Peptide’s Certificate of Analysis

Enter your peptide batch number printed on your vial’s label to instantly view third-party testing chromatograms, MS reports, and purity indices.

INSTANT HPLC TRANSPARENCY

Verify Your Peptide’s Certificate of Analysis

Enter your peptide batch number printed on your vial’s label to instantly view third-party testing chromatograms, MS reports, and purity indices.

Every batch, four tests, documented

No lot is released until it clears third-party verification — documented in a COA that ships with every order.

Identity Test

Passed

Verifies the peptide’s sequence and structure so the correct compound is present in each vial.

Purity Test

Passed

Measures purity and concentration to confirm ≥99% purity on qualifying batches.

Sterility Test

Passed

Screens for bacteria, fungi, and other microorganisms to verify sterile handling.

Endotoxicity

Passed

Tests for lipopolysaccharides (LPS) to ensure endotoxin levels stay within research limits.

GHK-Cu

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