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$179.00
4.98/5 · 500+ researcher reviews
$179.00
$179.00
2 vials · $85.44 per vial
$179.00
Guaranteed quality
2–3 business days
30-day money-back promise
Every order is backed by full reship or refund coverage, including international shipments. All products are produced under documented lab procedures and ship with batch-verified COAs — what’s on the label is exactly what’s in the vial.
Gen Three GLP is a synthetic investigational peptide developed as a multi-pathway agonist. It is currently being studied for its potential effects on receptor-mediated signaling, molecular dynamics, and endocrine function in preclinical research models. By activating multiple target receptor subtypes, DP3-R demonstrates broad systemic effects under investigation for their relevance in endocrine and pathway-level research.
The development of Gen Three GLP builds on decades of research into peptide signaling science. Early studies with single pathway agonists established their role in downstream signaling and receptor activity. Subsequent research expanded to dual agonist frameworks, paving the way for DP3-R, which uniquely integrates three pathway targets. This multi-agonist design reflects a new direction in peptide research aimed at investigating broader receptor-mediated modulation in preclinical laboratory settings.
CAS #: 2381089-83-2
Molecular Formula: C₂₂₁H₃₄₂N₄₆O₆₈
Molecular Weight: 4845.44 g/mol
PubChem ID: 474492335
Quantity: 10 mg per vial
Format: Sublingual liquid
Purity: ≥99% (qualifying batches)
Gen Three GLP has been examined in endocrine and systemic models, with studies highlighting its influence on receptor binding kinetics, downstream signaling cascades, lipid pathway dynamics, and integrated endocrine pathways. Research also points to its role in multi-system signaling and pathway characterization in preclinical and laboratory settings.
Endocrine: Receptor binding, signaling, cascade
Pathway: Target subtypes, modulation, dynamics
Vascular: Lipid pathways, hepatic signaling, markers
Systemic: Multi-pathway signaling, resilience, characterization
Together, these findings suggest broad experimental potential for Gen Three GLP across endocrine, vascular, and systemic models. By engaging multiple pathway targets, it provides a versatile research platform for studying downstream signaling cascades and integrated molecular responses across diverse biological systems.
Jastreboff A.M. et al., New England Journal of Medicine, 2023
A synthetic triple-receptor agonist peptide, supplied for laboratory research in Rize's needle-free sublingual carrier.
GLP-3 RETA is studied as a triple agonist — engaging three distinct metabolic receptors simultaneously. For research context only.
Glucagon-like peptide-1 receptor activation is studied for its role in gastric emptying and nutrient-stimulated signaling.
Glucose-dependent insulinotropic polypeptide receptor activation is examined in insulin-sensitivity and lipid-metabolism models.
Glucagon receptor activation is investigated for its role in energy expenditure and thermogenesis pathways.
| Compound | Retatrutide |
| Research designation | LY3437943 |
| Peptide length | 39 amino acids |
| Molecular weight | ~2,124 g/mol |
| Mechanism | GLP-1 / GIP / glucagon triagonist |
| Quantity | 10 mg per vial |
| Format | Sublingual liquid |
| Purity | ≥99% (qualifying batches) |
Formulated with a Submagna, SNAC, DMSO and modified-Penetratin permeation matrix for needle-free delivery.
Every batch is third-party tested with HPLC and mass spectrometry for identity, purity, and endotoxins.
Orders dispatched same-day from our AUS and U.S. facility with tracked, temperature-considered shipping.
No lot is released until it clears third-party verification — documented in a COA that ships with every order.
Verifies the peptide's sequence and structure so the correct compound is present in each vial.
Measures purity and concentration to confirm ≥99% purity on qualifying batches.
Screens for bacteria, fungi, and other microorganisms to verify sterile handling.
Tests for lipopolysaccharides (LPS) to ensure endotoxin levels stay within research limits.
Everything you need to know about our products and processes.
Enter your peptide batch number printed on your vial’s label to instantly view third-party testing chromatograms, MS reports, and purity indices.
Enter your peptide batch number printed on your vial’s label to instantly view third-party testing chromatograms, MS reports, and purity indices.
No lot is released until it clears third-party verification — documented in a COA that ships with every order.
Verifies the peptide’s sequence and structure so the correct compound is present in each vial.
Measures purity and concentration to confirm ≥99% purity on qualifying batches.
Screens for bacteria, fungi, and other microorganisms to verify sterile handling.
Tests for lipopolysaccharides (LPS) to ensure endotoxin levels stay within research limits.
